Historic Southwest Vacations from $673
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Your Historic Southwest Vacation
Book a Historic Southwest vacation package and immerse yourself in the rhythm and vibe of this interesting neighborhood. With all your travel plans taken care of, the only thing you need to worry about here is having a great time. When it's time to head out and explore, you'll find lots of big-name attractions nearby including Mayo Civic Center, Apache Mall and Rochester Recreation Center. Visit one, two or all during your trip to Historic Southwest. Stop dreaming and start doing. When it's time to book your next vacation to Historic Southwest, Expedia is here to help.
The Latest Historic Southwest Vacation Packages
Price found within the past 48 hours. Click for updated prices.
AmericInn by Wyndham Rochester Near Mayo Clinic
Price was $696, price is now $673 per person
$673
per person
Sep 22 - Sep 24
found 1 day ago
Roundtrip non-stop flight included
Louisville (SDF) to Rochester (RST)
8/10 Very Good! (1,362 reviews)
Clean room and bathroom. Budget-friendly. Comfortable beds. The refrigerator was not cold. My 15 yo daughter and I only needed to stay for one night, so it was not a big deal. There was only one usable outlet near the bed, which prevented more than one person to plug anything in next to the bed. My daughter had an issue with that.
Reviewed on Jul 2, 2026
The Towers At Kahler Grand Hotel
Downtown Rochester
Price was $1,149, price is now $1,081 per person
$1,081
per person
Sep 22 - Sep 24
found 1 day ago
Roundtrip non-stop flight included
Louisville (SDF) to Rochester (RST)
9.6/10 Exceptional! (114 reviews)
Everyone was very helpful throughout our stay. Our Tower Suite was wonderful and amenities were great.
Reviewed on Jun 29, 2026
The Berkman
Folwell
Price was $837, price is now $797 per person
$797
per person
Sep 22 - Sep 24
found 1 day ago
Roundtrip non-stop flight included
Louisville (SDF) to Rochester (RST)
9.6/10 Exceptional! (419 reviews)
Wonderful property with a few caveats. The amenities are great, and the location is ideal for St Mary’s. The apartment is large and parking safe and easy. That said, the bed is very hard and pillows aren’t great. The vents also hit directly on your face in the bed, so that was hard to get used to. I would stay again but only if I brought my own pillows and blankets
Reviewed on Jul 2, 2026
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Kutzky Park
Price was $778, price is now $743 per person
$743
per person
Sep 22 - Sep 24
found 1 day ago
Roundtrip non-stop flight included
Louisville (SDF) to Rochester (RST)
9.2/10 Wonderful! (520 reviews)
The hotel appeared to be under construction, with yellow tape hanging everywhere. The front desk sells snacks but didn't take cash (and was a bit rude about it). The gym has no sauna and the hot tub isn't very hot.
The breakfast was great and the room was clean. It's right across from the Mayo Clinic, a convenient walk across the street.
Reviewed on Jun 12, 2026
Kahler Grand Hotel
Downtown Rochester
Price was $778, price is now $755 per person
$755
per person
Sep 22 - Sep 24
found 1 day ago
Roundtrip non-stop flight included
Louisville (SDF) to Rochester (RST)
8.4/10 Very Good! (2,161 reviews)
What an incredible hotel. From the Valet to the Front Desk, and the restaurants…. INCREDIBLE! The access to downtown and the underground mall are a great treat. Had no idea we could go down the elevator and right j in not Mayo Clinic without going outside! Big bonus!! Do it now! I will be….
Reviewed on Jul 2, 2026
Where to stay in Historic Southwest
Find the best Historic Southwest areas and neighborhoods for the activities you enjoy most. Learn more about Historic Southwest
Downtown Rochester
3 out of top 10 points of interest in this area
4.5/5(253 area reviews)
If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Civic Theater are top sights worth seeing.
Historic Southwest Hotel Deals
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
401 6th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $118 total per night from Jul 19 to Jul 20
$118 total
Jul 19 - Jul 20
Total with taxes and fees
8.6/10 Excellent! (1,004 reviews)
"Room was dated and waste can had not been emptied. Front desk staff were not especially helpful."
Reviewed on Jul 2, 2026
Hilton Garden Inn Rochester Downtown, MN
225 S Broadway Rochester MN
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $131 total per night from Jul 31 to Aug 1
$131 total
Jul 31 - Aug 1
Total with taxes and fees
8.8/10 Excellent! (920 reviews)
"Excellent staff, quick to serve, and kind. And we love the convenience of the skyway to Mayo! Best hotel for Mayo patients."
Reviewed on Jul 3, 2026
Kahler Grand Hotel
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $148 total per night from Jul 6 to Jul 7
$148 total
Jul 6 - Jul 7
Total with taxes and fees
8.4/10 Very Good! (2,178 reviews)
"What an incredible hotel. From the Valet to the Front Desk, and the restaurants…. INCREDIBLE! The access to downtown and the underground mall are a great treat. Had no idea we could go down the elevator and right j in not Mayo Clinic without going outside! Big bonus!! Do it now! I will be…."
Reviewed on Jul 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Historic Southwest attractions
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.