
Historic Southwest Vacations from $673
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Your Historic Southwest Vacation
Book a Historic Southwest vacation package and immerse yourself in the rhythm and vibe of this interesting neighborhood. With all your travel plans taken care of, the only thing you need to worry about here is having a great time. When it's time to head out and explore, you'll find lots of big-name attractions nearby including Mayo Civic Center, Apache Mall and Rochester Recreation Center. Visit one, two or all during your trip to Historic Southwest. Stop dreaming and start doing. When it's time to book your next vacation to Historic Southwest, Expedia is here to help.
The Latest Historic Southwest Vacation Packages

AmericInn by Wyndham Rochester Near Mayo Clinic
Reviewed on Jul 2, 2026

The Towers At Kahler Grand Hotel
Reviewed on Jun 29, 2026

The Berkman
Reviewed on Jul 2, 2026

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Reviewed on Jun 12, 2026

Kahler Grand Hotel
Reviewed on Jul 2, 2026
Where to stay in Historic Southwest

Downtown Rochester
If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Civic Theater are top sights worth seeing.
Historic Southwest Hotel Deals

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
"Room was dated and waste can had not been emptied. Front desk staff were not especially helpful."
Reviewed on Jul 2, 2026

Hilton Garden Inn Rochester Downtown, MN
"Excellent staff, quick to serve, and kind. And we love the convenience of the skyway to Mayo! Best hotel for Mayo patients."
Reviewed on Jul 3, 2026

Kahler Grand Hotel
"What an incredible hotel. From the Valet to the Front Desk, and the restaurants…. INCREDIBLE! The access to downtown and the underground mall are a great treat. Had no idea we could go down the elevator and right j in not Mayo Clinic without going outside! Big bonus!! Do it now! I will be…."
Reviewed on Jul 2, 2026





















